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12 Apr 2025 - 04:18 pm

Exposure to phthalates during pregnancy can affect a newborn’s brain development, study finds
порно жесток

Phthalates — the synthetic chemicals used in everyday products for food packaging, personal care, toys and more — have been linked to abnormal neurological development in infants.

Now, scientists may have discovered a biological pathway for how this phenomenon could occur. Researchers found that in utero exposure to phthalates is linked with altered metabolism of neurotransmitters and amino acids involved in brain maturation, according to a study published Wednesday in the journal Nature Communications.

The report is the first to use untargeted metabolomics — the study of all small molecules or metabolites in a biological system — to connect a mother’s phthalate exposure to a newborn’s metabolites, and those metabolites to neurological development, said senior study author Dr. Donghai Liang via email.
“This represents an important step forward in understanding how prenatal chemical exposures shape infant development at the molecular level,” added Liang, an associate professor of environmental health at Emory University’s Rollins School of Public Health in Atlanta.

First introduced in the 1920s, phthalates are used to make plastics softer and more flexible, primarily in polyvinyl chloride (PVC) products such as vinyl flooring, medical devices, children’s toys, food packaging or shower curtains. The chemicals also help lubricate substances and carry fragrances in various personal care products including deodorant; nail polish; perfumes; hair gels, sprays or shampoos; soaps; and body lotions.

Phthalates are also endocrine disruptors that have been linked to preterm birth, infant genital abnormalities, childhood obesity, asthma, cancer, cardiovascular issues, and low sperm count and testosterone in men.

“We conducted this study because phthalates are everywhere in our daily lives,” Liang said, hence their nickname “everywhere chemicals.”

Harming infant health
The findings are based on mother-newborn pairs enrolled in the Atlanta African American Maternal-Child Cohort between 2016 and 2018. In urine samples collected from 216 mothers between eight weeks and 14 weeks of gestation at visit one and 145 participants between 24 and 30 weeks’ gestation at visit two, the authors measured eight phthalate metabolites. Participants were around age 24 on average, and their levels of some phthalate metabolites were higher than the average determined by the National Health and Nutrition Examination Survey.

Within a day or two of birth, the authors collected the babies’ blood via a heel stick.

The team found prenatal phthalate levels were associated with lower levels of tyrosine, an amino acid and precursor to the thyroid hormone thyroxine. Thyroxine was also abnormally low in those with in utero phthalate exposure, and low thyroxine has been previously associated with greater vulnerability to illness and neurodevelopmental issues in newborns, the authors said. Tyrosine is also a precursor to the neurotransmitters dopamine, norepinephrine and epinephrine, all of which partly contribute to the body’s fight-or-flight response. Low levels of these neurotransmitters can lead to various problems, including anxiety, depression and trouble focusing.

Prenatal phthalate exposure was also linked with lower levels of the essential amino acid tryptophan, which converts into 5-hydroxytryptophan (or 5-HTP), which then turns into serotonin. Both 5-HTP and serotonin were also low. Serotonin has several critical roles in the body, including mood regulation, sleep, learning, memory, digestion and the body’s response to stress. Previous research has linked low serotonin with mood disorders such as depression and anxiety, sleep problems, and digestive issues.

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12 Apr 2025 - 12:33 am

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11 Apr 2025 - 11:16 pm

Здравствуйте, прочитал пост девушки об этой организации и не только этой под руководством директора Абросимова В.Н.
Сам пост здесь https://telegra.ph/Otzyv-o-moshennikah-Armor-ZMI-gorod-Marks-MP-orbita-TD-ZKS-01-15. Хочу поделиться своей историей. Сам отзыв я оставил здесь: https://rateorg.com/57688. Также читайте отзывы про эти конторы
https://reviews.yandex.ru/shop/td-zks.ru
https://2gis.ru/engels/firm/70000001026666256/tab/reviews
https://xn--80aadjlwktfy.xn--p1ai/avto_i_transport/avtomobili/7993-nedobrosovestnyy-postavschik.html (здесь от 2013 года отзыв, они уже более десяти лет обманывают людей, немыслимо!!!)
https://vk.com/wall-56628241_882
Отзыв
Как только начал работать с этой компанией, сразу стало понятно, что это не более чем обычная шарага. ООО «Армор-ЗМИ» это, по сути, мелкая организация с ужасным менеджментом. Когда я заказал металлические конструкции, думал, что получу что-то хотя бы на уровне. Ну а что можно ожидать от фирмы с уставным капиталом в 10 000 рублей? Не ожидал ничего особенного, но такой откровенной лажи даже не мог себе представить.
Сначала все казалось норм, но как только пошел процесс, всё пошло по наклонной. Сроки доставки не просто затягиваются, они просто исчезают! Звонишь, пытаешься понять, что происходит, а они кидают отговорки и постоянно на что-то ссылаются то машины нет, то сотрудников. Сами металлоконструкции вообще не соответствуют заявленному качеству. Кажется, что они просто взяли дешёвое железо и, не утруждая себя дополнительной обработкой, отправили мне. Все криво, косо, как будто на коленке сделано.
Генеральный директор, Вадим Абросимов, вообще отдельная история. Звоню, пытаюсь поговорить, а на том конце трубки человек, который по делу вообще ничего сказать не может. Приятель, который посоветовал эту компанию, признался, что лизинговые автомобили, которые они арендуют, это их единственная реальная активность. Продукция? Да никто ей не занимается!
Так что если хотите купить что-то приличное и не угробить проект держитесь подальше от этой шараги. Самое страшное такие компании продолжают работать, потому что не знаю, кто реально хочет связываться с ними на долгий срок.
Не наступайте на те же грабли. Будьте внимательны. Да, с позволения девушки, которая писала отзыв, я оставлю контакты всех организаций где так бесславно трудится недобросовестный директор Абросимов В.Н.:
Сайт TD-zks.ru телефоны 89370291117, 88453544710, почта info@td-zks.ru. ИНН 6449075860
Сайт Mp-orbita.ru +7 (927) 227-13-48, почта info@mp-orbita.ru. ИНН 6449104817
Сайт Запчасти-к-станкам.рф телефоны 89372555454, 89376333838 почты armor.zmi@mail.ru,89372555454@yandex.ru. юрлицо АрморЗМИ ИНН 6449102915
Сайт Запчасти-для-станков.рф телефоны 88453711348, 89272281348 почта mettex-64@mail.ru. ИНН 6449104817
Будьте очень внимательны, если наткнулись на данные организации - бегите без оглядки, не теряйте деньги и время. Спасибо за внимание.
https://telegra.ph/Otzyv-o-moshennikah-Armor-ZMI-gorod-Marks-direktor-Abrosimov-VN-01-16


https://tinyurl.com/moshenniki
Обманщики с деталями к станкам
Отзыв о Запчасти-для-станков.рф - кидают на деньги
Отзыв о Директор Абросимов В.Н. - жулики
Отзыв о ИНН 6449075860 - кидают на деньги
Отзыв о МП Орбита Энгельс -- обманщики
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